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Inulin-type fructans supplementation improves glycemic control for the prediabetes and type 2 diabetes populations: results from a GRADE-assessed systematic review and dose-response meta-analysis of 33 randomized controlled trials Inulin-type fructans;Glycemic control; Type 2 diabetes; Prediabetes; Meta-analysis

2023-03-29

The aim of this meta-analysis of randomized controlled trials was to assess the effects of ITF supplementation on glycemic control. Our analyses confrmed that these four main glycemic indicators were signifcantly reduced by ITF supplementation, particularly in the prediabetes and T2DM population.

Inulin-type fructans Glycemic control Type 2 diabetes Prediabetes Meta-analysis
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The effect of enriched chicory inulin on liver enzymes, calcium homeostasis and hematological parameters in patients with type 2 diabetes mellitus Type 2 diabetic mellitus; Chicory; Liver enzymes; Calcium homeostasis; Hematological parameters

2022-08-10

Type 2 diabetic mellitus (T2DM) as one of the main causes of morbidity and mortality is associated with immune system disturbances and metabolic abnormalities. In the current study we aimed to evaluate the effects of enriched chicory inulin supplementation on liver enzymes, serum calcium and phosphorous concentrations and hematological parameters in patients with T2DM.

Type 2 diabetic mellitus Chicory Liver enzymes Calcium homeostasis Hematological parameters
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Metabolic Effects of a Diet with Inulin-Enriched Pasta in Healthy Young Volunteers Blood lipids, fiber, fuctosamine, gastric emptying, glucose, inulin, metabolic syndrome.

2023-03-27

Different lines of evidence suggest that higher intake of fiber may somehow protect against metabolic syndrome. The prebiotic inulin has widely been studied in relation to its putative beneficial effects on lipid and glucose metabolism. Therefore, adding inulin to diet may be a suitable strategy to prevent metabolic syndrome. Aim of the present study was to evaluate the effects of the daily consumption of inulin-enriched pasta on lipid and glucose metabolism as well as on gastrointestinal motility in young healthy subjects.

Blood lipids fiber fuctosamine gastric emptying glucose inulin metabolic syndrome.
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Inulin controls inflammation and metabolic endotoxemia in women with type 2 diabetes mellitus: a randomized-controlled clinical trial Cytokines, lipopolysaccharide, prebiotics

2022-08-10

There is limited evidence on the effects of prebiotics on inflammation. Therefore, the aim of this study was to evaluate the effects of inulin supplementation on inflammatory indices and metabolic endotoxemia in patients with type 2 diabetes mellitus. The participants included diabetic females (n ¼ 49). They were divided into an intervention group (n ¼ 24) as well as a control group (n ¼ 25) and received 10 g/d inulin or maltodextrin for 8 weeks, respectively. Fasting blood sugar (FBS), HbA1c, insulin, high-sensitive C-reactive protein (hs-CRP), tumor necrosis factor-alpha (TNF-a), interleukin-10 (IL-10), and plasma lipopolysaccharide (LPS) were measured pre and post intervention.

Cytokines lipopolysaccharide prebiotics
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Effects of oligofructose-enriched inulin prebiotic supplementation on the lipid profile and inflammation in women with type 2 diabetes: A randomized controlled trial inflammation; inulin; type 2 diabetes

2022-08-10

Considering the high prevalence of diabetes and developing cardiovascular diseases through dyslipidemia and inflammation in type 2 diabetic patients, the aim of the present study was to investigate the effects of oligofructose-enriched inulin on serum lipid concentrations and inflammation in women with type 2 diabetes.

inflammation inulin type 2 diabetes
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