Inulin controls inflammation and metabolic endotoxemia in women with type 2 diabetes mellitus: a randomized-controlled clinical trial Cytokines, lipopolysaccharide, prebiotics
There is limited evidence on the effects of prebiotics on inflammation. Therefore, the aim of this study was to evaluate the effects of inulin supplementation on inflammatory indices and metabolic endotoxemia in patients with type 2 diabetes mellitus. The participants included diabetic females (n ¼ 49). They were divided into an intervention group (n ¼ 24) as well as a control group (n ¼ 25) and received 10 g/d inulin or maltodextrin for 8 weeks, respectively. Fasting blood sugar (FBS), HbA1c, insulin, high-sensitive C-reactive protein (hs-CRP), tumor necrosis factor-alpha (TNF-a), interleukin-10 (IL-10), and plasma lipopolysaccharide (LPS) were measured pre and post intervention.